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September 2016

Volume 3  Issue 3

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Research Article

How to Collect Cord Blood?

Leanza V, Pafumi C*, Leanza G, D’Agati A

A lot of research has been performed all over the world on umbilical cord blood (UCB), and many UCB banks have been instituted in the U.S.A. and Europe, since Gabutti, for the first time, collected and isolated several foetal haematopoietic progenitor cells from the residual placental blood, after delivery and ligation of the umbilical cord. In Italy, also, UCB banks belonging to the GRACE group of Milan connected to the European Netcord have been established. Recently, a new UCB bank has been instituted in Sicily, particularly in Sciacca.

 

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Case Report

Noonan Syndrome - Cardiac Decompensation due to severe Hypertrophic Obstructive Cardiomyopathy in Pregnancy

Sarah Lovell, Jacadi Bignami, Nora Bassiouini, Lauren Yu*, Afshan Hameed

Noonan Syndrome (NS) is an autosomal dominant disorder with complete penetrance and variable expressivity that affects 1:1000 to 1:2500 live births [1]. It is characterized by facial dysmorphism, short stature, heart defects, skeletal malformations, bleeding diatheses, and mild mental delay. Congenital cardiac defects are encountered in more than 80% of cases, with the majority of cardiac defects being pulmonary stenosis and hypertrophic cardiomyopathy [2]. Literature remains sparse with regards to management of NS in pregnancy.

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Case Report

Angiomyolipomas As A Cause of Abnormal Uterine Bleeding In A Patient with Tuberous Sclerosis

Lara F B Harvey MD, Kevin K Kumar PhD, Mohamed Mokhtar Desouki MD PhD, Ted L Anderson MD PhD*

Tuberous Sclerosis Complex (TSC) is an autosomal dominant disorder characterized by benign tumors in multiple organs, most frequently the skin and kidneys. This is associated with functional loss of tumor suppressors TSC1 and TSC2. Angiomyolipomas (AMLs) are usually slow-growing hamartomas rich in muscle, fat, and blood vessels that are present in approximately 80% of patients with TSC . These tumors exhibit high-grade mitotic activity, pleomorphism, and necrosis , making them susceptible to rupture and hemorrhage . While distribution of angiomyolipomas has been well described in nervous, renal, hepatic, cardiovascular, and integumentary systems, conspicuously few cases of angiomyolipoma involving the uterus have been reported in this patient population.

 

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Research article

Is Middle Cerebral Artery Doppler Velocimetry Good Predictor of Fetal wellbeing in Fetuses with Non-Reactive NST

Mehmet Çınar MD*, Rıfat Taner Aksoy MD, Ali İrfan Güzel MD, Omer Hamid Yumuşak MD, Aykut Kadıoğlu MD, Yasemin Taşçı MD

In this descriptive longitudinal study, we aimed to evaluate the predictive role of middle cerebral artery doppler velocimetry in assessing non-reactive non-stress test (NST). 148 cases with recovered non-reactive NST group were classified as group 1 and 151 cases persistent non-reactive NST as group 2. Data collected and age, GW (gestational weeks), gravidity, parity, middle cerebral artery doppler velocimetry, non-stress test (NST) were evaluated of each patient. MCA doppler PI levels were significantly low in group 2 (p < 0.05).

 

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