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December 2015

Volume 2  Issue 4

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Case Report

Myasthenia Crisis in Pregnancy

Roopan K. GILL MD*, Tung Thanh Cao NGUYEN MD, FRCPC, Pierre J. HUARD MD, FRCSC, Hisham A. KHALIL MD, FRCSC

Myasthenia Gravis (MG) is an autoimmune disorder of the neuromuscular junction characterized by fluctuating weakness of skeletal muscles. It is caused by autoantibodies against post synaptic acetylcholine receptor (AChR). In pregnancy, myasthenia gravis has both maternal and fetal implications, and can manifest in various degrees of weakness and fatigability of skeletal muscles. Respiratory failure is a life threatening complication of this rare disorder.

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Case Report

Hydatid Disease of Liver during Pregnancy: Report of Two Cases and Review of Literature

Emre Ekmekci, Emine Demirel*, Servet Gencdal, Sefa Kelekci

Echinococcosis or hydatid disease is parasitary infection disease and it is caused by the larval form of Echinococcus Granulosus. It’s primarily a disease of sheep and cattle. Human beings are accidental hosts. Cystic lesions are constituted by parasite, most commonly in the liver and also in other organs. The disease is rare during pregnancy. Main treatment is surgical and medical treatment is necessary in selected cases. So treatment should be individualized for each patient. The diagnosis of hydatid disease of liver is not difficult but management of pregnant women poses some problems. Recurrence of hydatid disease seems more common during pregnancy.

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Research Article

Self-Administered Pap Smear, Selfpap®: An Acceptable and Effective Cervical Cytology Sampling Method

Fernando O. Recio, MD, Lauren E. Spoo, MS4*, Paul Crawford, MD, Tracy J. Slager, DO, Jean Marie Maleck, MD, Samantha Butler, MD, Joseph A. Migliozzi, MD, PhD

Cervical cancer remains pervasive even in much of the developed world despite advances in prevention and early detection. Screening with the traditional Papanicolau (Pap) smear presently requires that trained professionals perform it, usually in the setting of an office visit, which, for a variety of reasons, can present as a barrier to universal screening. The Self- Pap® kit, which allows women to self-collect cervical cytology specimens, was designed as an alternative to the traditional Pap test for those who would not otherwise undergo routine screening. Our objective was to evaluate the patient acceptability of the SelfPap® kit and to compare diagnostic accuracy of the SelfPap® cervical-collection method for detecting abnormal cervical cytology assessed by a cervical physician-obtained sample.

 

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Case Report

Dangerous Methotrexate-Indispensable Abdominal Pregnancies in A Developed Country

Tatsuji Hoshino*, Taito Miyamoto, Nobutaka Hayashi, Kazuhiko Uematsu, Hiroyuki Tomita, Takuya Aoki, Shinya Yoshioka

In normal pregnancy, a fertilized egg is implanted in the endometrial gland area of the uterine corpus. In ectopic pregnancy (EP), however, implantation occurs elsewhere, including in the tubal, ovarian, cesarean scar, cervical or abdominal area. EPs comprise 1% of all pregnancies, and abdominal pregnancies (APs) comprise 1% of all EPs; APs thus account for only 0.01% of all pregnancies and are considered very rare. Although most APs show similar symptoms and signs to other EPs during the early stages, some undergo abrupt clinical course and massive intra-abdominal bleeding with rupture of the pregnancy mass because the pregnancy contents are not covered by the tube or uterus.

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